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Light Modulates Important Pathogenic Determinants and Virulence in ESKAPE Pathogens Acinetobacter baumannii, Pseudomonas aeruginosa, and Staphylococcus aureus

By |2021-02-27T08:46:19+00:00February 27th, 2021|

ABSTRACT Light sensing has been extensively characterized in the human pathogen Acinetobacter baumannii at environmental temperatures. However, the influence of light on the physiology and pathogenicity of human bacterial pathogens at temperatures found in warm-blooded hosts is still poorly understand. In this work, we show that Staphylococcus aureus, Acinetobacter baumannii, and Pseudomonas aeruginosa (ESKAPE) priority pathogens, which have been recognized by the [...]

Association between ambient air pollution and development and persistence of atopic and non‐atopic eczema in a cohort of adults

By |2021-02-27T08:46:18+00:00February 27th, 2021|

Background There is limited information on risk factors for eczema in adults.Recent evidence suggeststhat air pollution may be associated with increased incidence of eczema in adults. We aimed to assess this possible association. Methods Ambientair pollution exposures (distance from a major road, nitrogen dioxide [NO2], fine particulate matter with an aerodynamic diameter ≤2.5 µm [PM2.5]) were assessed [...]

We Need a Global Outbreak Investigation Team—Now

By |2021-02-27T08:46:18+00:00February 27th, 2021|

THIS WEEK,a much anticipated fact-finding mission into the origins of Covid-19 returned from a month-long field visit to China. The team of scientists appointed by the World Health Organization are currently writing up their findings, which will be published in a summary report next week, with a full report expected to follow sometime after that. But on Tuesday, at [...]

Aerosol filtration efficiency of household materials for homemade face masks: Influence of material properties, particle size, particle electrical charge, face velocity, and leaks

By |2021-02-27T08:46:14+00:00February 27th, 2021|

As a consequence of the COVID-19 pandemic caused by the SARS-CoV-2 virus, the widespread daily use of face masks is promoted worldwide. Particle-size dependent filtration efficiencies (FE; dp = 30 nm–10 µm), applying a particle counting approach, and additionally pressure drops (Δp) were determined for 44 samples of household materials and several medical masks.     Pcharmedlightph/iStock Read more… Download [...]

Dizzy spells when you stand up: When should you worry?

By |2021-02-27T08:46:11+00:00February 27th, 2021|

It’s a common phenomenon with an uncommon name: orthostatic hypotension. It just means that when you shift from lying down or sitting to standing, your blood pressure drops and you momentarily feel a little woozy. That’s because blood pools in your legs temporarily when you stand up, and it takes the body a moment to [...]

Breast cancer overtakes lung as most common cancer-WHO

By |2021-02-25T08:24:34+00:00February 25th, 2021|

GENEVA (Reuters) -Breast cancer has overtaken lung cancer as the most common form of the disease, accounting for nearly 12% of new cases each year worldwide, the World Health Organisation said on Tuesday. “For the first time, breast cancer now constitutes the most commonly occurring cancer globally,” Andre Ilbawi, a cancer specialist at the WHO, told [...]

Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance

By |2021-02-24T08:11:56+00:00February 24th, 2021|

Background Troponin elevation is common in hospitalized COVID-19 patients, but underlying aetiologies are ill-defined. We used multi-parametric cardiovascular magnetic resonance (CMR) to assess myocardial injury in recovered COVID-19 patients. Methods and results One hundred and forty-eight patients (64 ± 12 years, 70% male) with severe COVID-19 infection [all requiring hospital admission, 48 (32%) requiring ventilatory support] and troponin [...]

Predictors of hospital discharge and mortality in patients with diabetes and COVID-19: updated results from the nationwide CORONADO study

By |2021-02-24T08:11:55+00:00February 24th, 2021|

Aims/hypothesis This is an update of the results from the previous report of the CORONADO (Coronavirus SARS-CoV-2 and Diabetes Outcomes) study, which aims to describe the outcomes and prognostic factors in patients with diabetes hospitalised for coronavirus disease-2019 (COVID-19). Methods The CORONADO initiative is a French nationwide multicentre study of patients with diabetes hospitalised for COVID-19 with a [...]

NIH funds study to evaluate remdesivir for COVID-19 in pregnancy

By |2021-02-24T08:11:54+00:00February 24th, 2021|

A new study funded by the National Institutes of Health will evaluate the effects of remdesivir in pregnant women who have been prescribed the drug to treat COVID-19. The study, which will be conducted at 17 sites in the continental United States and Puerto Rico, aims to determine how pregnant women metabolize the drug and [...]