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The Infectious Nature of Patient-Generated SARS-CoV-2 Aerosol

By |2020-07-31T18:51:36+00:00July 31st, 2020|

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission causing coronavirus disease 2019 (COVID-19) may occur through multiple routes. We collected aerosol samples around six patients admitted into mixed acuity wards in April of 2020 to identify the risk of airborne SARS-CoV-2. Measurements were made to characterize the size distribution of aerosol particles, and size-fractionated, aerosol [...]

Adverse pregnancy outcomes and risk of later allergic rhinitis—Nationwide Swedish cohort study

By |2020-07-31T18:51:32+00:00July 31st, 2020|

Background Perinatal conditions may be associated with future allergic disease; however, data are conflicting and incomplete for childhood allergic rhinitis (AR). The aim of this study was to examine pregnancy outcome (cesarean delivery, preterm birth, low birthweight) and offspring AR as defined by national registers. Methods Nationwide longitudinal cohort study using prospectively recorded register data [...]

Benefits and risks of the Sanofi-Pasteur dengue vaccine: Modeling optimal deployment

By |2020-07-31T18:51:29+00:00July 31st, 2020|

Abstract The first approved dengue vaccine has now been licensed in six countries. We propose that this live attenuated vaccine acts like a silent natural infection in priming or boosting host immunity. A transmission dynamic model incorporating this hypothesis fits recent clinical trial data well and predicts that vaccine effectiveness depends strongly on the age group [...]

Collaborating in the Fight for Health

By |2020-07-31T18:51:21+00:00July 31st, 2020|

The Partnership to Fight Infectious Disease (PFID) is a group of patients, providers, community organizations, business and labor groups, and health policy experts working to advance awareness and action on antimicrobial resistance. As an initiative of the Partnership to Fight Chronic Disease, PFID is focusing on  the impact of this growing issue on our population and health [...]

Civil War vaccination kits, discovered in a drawer, yield genetic clues to how smallpox was defeated

By |2020-07-31T17:48:31+00:00July 31st, 2020|

As the world anxiously pins its hopes on vaccines to halt the coronavirus pandemic, scientists are still learning from the first global scourge to be eradicated by vaccination. Ancient-DNA sleuths analyzing Civil War-era artifacts with 21st-century sequencing techniques have recreated five genomes of viral vaccines mustered to fight smallpox in the 1860s, finding they were quite [...]

Promising early findings for 2 more COVID-19 vaccines

By |2020-07-31T17:48:29+00:00July 31st, 2020|

In a pair of promising developments today, researchers from Oxford University and another group from China reported in The Lancet that two different adenovirus-vectored COVID-19 vaccines prompted an immune response and appeared to be safe, paving the way for efficacy trials.  Meanwhile, the global COVID-19 total passed 14.5 million today and is at 14,604,077 cases with [...]

Do houseplants really improve air quality?

By |2020-07-31T17:48:27+00:00July 31st, 2020|

Gardening is full of received wisdom that is treated as gospel and handed down across the generations – from putting a layer of crocks at the bottom of pots for drainage, to the back-breaking work of Victorian “double-digging” to improve soil structure. But when tested scientifically much of this old-school advice turns out not to [...]

Personal perception can be an important indicator for early detection of Alzheimer’s

By |2020-07-31T17:48:25+00:00July 31st, 2020|

A research team led by the German Center for Neurodegenerative Diseases (DZNE) concludes that personal perception can be an important indicator for the early detection of Alzheimer’s disease. In a new study involving 449 older adults, published in Neurology®, the medical journal of the American Academy of Neurology, the scientists report that individuals with subjectively felt [...]

Schools Should Prioritize Reopening in Fall 2020, Especially for Grades K-5, While Weighing Risks and Benefits

By |2020-07-30T18:41:43+00:00July 30th, 2020|

WASHINGTON — Weighing the health risks of reopening K-12 schools in fall 2020 against the educational risks of providing no in-person instruction, school districts should prioritize reopening schools full time, especially for grades K-5 and students with special needs, according to a new report from the National Academies of Sciences, Engineering, and Medicine. Opening schools will benefit [...]

Trial data support dexamethasone, but not hydroxychloroquine, for COVID-19

By |2020-07-30T18:41:41+00:00July 30th, 2020|

Data from a large randomized controlled trial in the United Kingdom showing a benefit from use of the steroid dexamethasone in hospitalized COVID-19 patients was released today in the New England Journal of Medicine (NEJM), while two more studies show no benefit for the malaria drug hydroxychloroquine. The NEJM data, which were originally reported in a press release in mid-June by [...]