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Very few severe allergic reactions tied to mRNA COVID vaccines

By |2021-03-24T14:02:10+00:00March 24th, 2021|

Acute allergic reactions occurred in 2.10% but anaphylaxis in only 0.025% of employees of two Boston hospitals who received their first dose of the Pfizer-BioNTech or Moderna COVID-19 vaccine, according to a research letter published yesterday in JAMA. Scientists from Massachusetts General Hospital and Brigham and Women’s Hospital administered email, text, phone, and smartphone app survey links to 64,900 [...]

Report: Economy rebound hinges on race between vaccines, variants

By |2021-03-24T14:02:07+00:00March 24th, 2021|

International economic projections have improved over the past months, but faster and more effective vaccine deployment is critical for getting key sectors back to prepandemic levels, the Organization for Economic Cooperation and Development (OECD) said in its latest update. In other developments, some hot spot countries reported rising hospitalization and intensive care unit (ICU) levels, [...]

Higher airborne pollen concentrations correlated with increased SARS-CoV-2 infection rates, as evidenced from 31 countries across the globe

By |2021-03-24T14:02:04+00:00March 24th, 2021|

Significance Coexposure to airborne pollen enhances susceptibility to respiratory viral infections, regardless of the allergy status. We hypothesized this could be also true for SARS-CoV-2 infections. To investigate this, we tested for relationships between SARS-CoV-2 infection rates and pollen concentrations, along with humidity, temperature, population density, and lockdown effects. Our unique dataset derives from 130 sites [...]

CARB-X IS FUNDING AFFINIVAX TO DEVELOP A NOVEL VACCINE TO PREVENT STAPHYLOCOCCUS AUREUS BACTERIAL INFECTIONS

By |2021-03-24T14:02:00+00:00March 24th, 2021|

(BOSTON) – CARB-X is funding Affinivax, a Cambridge, Massachusetts, USA, biotech, to develop a new vaccine that will prevent Staphylococcus aureus (S. aureus) bacterial infections, healthcare-associated infections that are a major health threat particularly to high-risk and older patients. No vaccine exists currently to prevent S. aureus infections, and there are limited treatment options, particularly with the spread of multidrug-resistant [...]

Dietary supplements during the COVID-19 pandemic: insights from 1.4M users of the COVID Symptom Study app – a longitudinal app-based community survey

By |2021-03-24T14:01:57+00:00March 24th, 2021|

Objectives Dietary supplements may provide nutrients of relevance to ameliorate SARS-CoV-2 infection, although scientific evidence to support a role is lacking. We investigate whether the regular use of dietary supplements can reduce the risk of testing positive for SARS-CoV-2 infection in around 1.4M users of the COVID Symptom Study App who completed a supplement use questionnaire. [...]

Death rate 64% higher with B117 COVID variant, study finds

By |2021-03-24T14:01:55+00:00March 24th, 2021|

The 28-day risk of death for the B117 COVID-19 variant was 64% higher than for previously circulating strains in people older than 30 years, a UK study finds. The study, led by University of Exeter researchers and published today in BMJ, involved community-based testing and death data from 54,906 matched pairs of participants who tested positive for COVID-19 [...]

Study adds more evidence of antibiotic overuse in COVID-19 patients

By |2021-03-24T14:01:52+00:00March 24th, 2021|

A new analysis of COVID-19 hospitalizations in the United States during the first 6 months of the pandemic shows that more than half resulted in a patient receiving an antibiotic. The study by researchers with the Pew Charitable Trusts’ antibiotic resistance project, also found that more than a third of admissions resulted in a patient being prescribed [...]

Biden to buy more COVID vaccine doses as stimulus bill passes

By |2021-03-24T14:01:48+00:00March 24th, 2021|

President Joe Biden is expected to announce that he is procuring an additional 100 million doses of the Johnson & Johnson (J&J) vaccine for the second half of 2021 during a meeting today with J&J and Merck executives. Last week, the two pharmaceutical giants formed a partnership to ramp up distribution of the single-dose J&J vaccine. “This [...]

Global COVID-19 activity shows continued variation

By |2021-03-24T14:01:44+00:00March 24th, 2021|

In its weekly snapshot of global pandemic activity, the World Health Organization (WHO) said yesterday that cases rose again last week, but not as steeply as the previous week, and that half of countries are reporting rises, as activity declines in the other half. Cases up in 3 WHO regions Last week, the WHO said cases were [...]

Improved empiric antibiotic prescribing for common infectious disease diagnoses using order sets with built-in clinical decision support in the emergency department

By |2021-03-24T14:01:43+00:00March 24th, 2021|

To the Editor—The Centers for Disease Control and Prevention estimated that in 2018, emergency departments (EDs) generated 12.7 million antibiotic prescriptions. 1 Up to 50% of these prescriptions may have been inappropriate with respect to antibiotic use or selection, dosing, and duration, based on outpatient prescribing estimates. 2 Improving prescribing is imperative, but historically, EDs are underrepresented in antibiotic [...]