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War-zone related stress may lead to changes in the microstructure of the brain

Military service members who have returned from theaters of war are at increased risk of mental health problems. But few studies have examined the physical effects that war-zone related stress may have on the structure of the brain.

‘Unstoppable’ bird flu epidemic causes growing alarm among Dutch farmers

With millions of chickens and ducks culled, farmers say only a vaccine can save the poultry sector from the ‘invisible enemy’

White House officials push boosters as BA.5 surge intensifies

Members of the White House COVID committee today urged people to get current with their COVID-19 vaccination and boosters, as a more transmissible Omicron variant expands its dominance across much of the country.

Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir

The SARS-CoV-2 main protease (Mpro) is a cysteine protease and a validated antiviral drug target.

Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths

This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database.

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to first-line azole antifungal drugs. However, despite its clinical importance, little is known about how susceptible patients acquire infection from drug-resistant genotypes in the environment.

Researchers find natural mechanism to sensitize cancer to immunotherapy

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

Much of the response to Covid-19 to date has been reactionary. Travel restrictions were implemented after a new variant had already breached the country. The use of higher-quality masks was recommended months after the emergence of increasingly more infectious variants — Alpha, Delta, then Omicron — and well after shortages had subsided. The need to ramp up the availability of rapid antigen tests was recognized during the sixth wave of Covid and amid the winter holidays.

Large-scale plasma proteomics can reveal distinct endotypes in chronic obstructive pulmonary disease and severe asthma

Chronic airway diseases including chronic obstructive pulmonary disease (COPD) and asthma are heterogenous in nature and endotypes within are underpinned by complex biology. This study aimed to investigate the utility of proteomic profiling of plasma combined with bioinformatic mining, and to define molecular endotypes and expand our knowledge of the underlying biology in chronic respiratory diseases.

Additional antibodies may protect against COVID

When we talk about antibodies against COVID-19, we tend to mean the so-called neutralizing antibodies, that offer protection by blocking the virus from invading our cells. Now, a new study from Lund University in Sweden has revealed that non-neutralizing antibodies may also be important in providing protection against COVID.

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