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Which particulate air pollution poses the greatest health risk?

By |2020-11-26T15:54:25+00:00November 26th, 2020|

Researchers at the Paul Scherrer Institute (PSI), together with colleagues from several other European institutions, have investigated whether particulate matter from certain sources can be especially harmful to human health. They found evidence that the amount of particulate matter alone is not the greatest health risk. Rather, it could be the so-called oxidative potential that [...]

Another side to cancer immunotherapy? Scientists investigate intratumoral B cells

By |2020-11-26T15:54:24+00:00November 26th, 2020|

Immunotherapies have transformed the treatment of several types of cancer over the last decade. Yet they focus on reactivating one arm of the immune system: cytotoxic T cells, which sniff out and kill tumor cells. In a new paper in Nature, scientists at Emory Vaccine Center and Winship Cancer Institute of Emory University (Winship) report on their [...]

Two studies focus on SARS-CoV-2 transmission in domestic cats, pigs

By |2020-11-26T15:54:23+00:00November 26th, 2020|

Two recently published studies from Kansas State University researchers and collaborators have led to two important findings related to the COVID-19 pandemic: Domestic cats can be asymptomatic carriers of SARS-CoV-2, but pigs are unlikely to be significant carriers of the virus. SARS-CoV-2 is the coronavirus responsible for COVID-19. “Other research has shown that COVID-19-infected human patients are transmitting [...]

COVID-19—Lessons Learned and Questions Remaining

By |2020-11-26T15:54:22+00:00November 26th, 2020|

In January 2020, the World Health Organization announced a Chinese outbreak of a respiratory illness caused by a novel coronavirus. Since that time the COVID-19 pandemic has caused more than 38 000 000 infections and 1 000 000 deaths worldwide [1], with no end yet in sight. This has been paralleled by an explosion of [...]

Whole-Genome Analysis of Clinical Vibrio cholerae O1 in Kolkata, India, and Dhaka, Bangladesh, Reveals Two Lineages of Circulating Strains, Indicating Variation in Genomic Attributes

By |2020-11-26T15:54:21+00:00November 26th, 2020|

ABSTRACT Vibrio cholerae serogroup O1 is responsible for epidemic and pandemic cholera and remains a global public health threat. This organism has been well established as a resident flora of the aquatic environment that alters its phenotypic and genotypic attributes for better adaptation to the environment. To reveal the diversity of clinical isolates of V. cholerae O1 in [...]

Trust researchers begin Hayfever study ahead of spring

By |2020-11-26T15:54:20+00:00November 26th, 2020|

A new study aims to determine whether a novel drug, given alongside an established immunotherapy treatment, will improve effectiveness, help shorten the treatment period for patients and prolong the effectiveness after the treatment course is completed. Hay fever affects approximately 13 million people in the UK and current treatments, including antihistamine tablets and nasal sprays, [...]

Shedding of SARS-CoV-2 in feces and urine and its potential role in person-to-person transmission and the environment-based spread of COVID-19

By |2020-11-26T15:54:20+00:00November 26th, 2020|

Abstract The recent detection of SARS-CoV-2 RNA in feces has led to speculation that it can be transmitted via the fecal-oral/ocular route. This review aims to critically evaluate the incidence of gastrointestinal (GI) symptoms, the quantity and infectivity of SARS-CoV-2 in feces and urine, and whether these pose an infection risk in sanitary settings, sewage [...]

The known unknowns of T cell immunity to COVID-19

By |2020-11-26T15:54:18+00:00November 26th, 2020|

INTRODUCTION The broad clinical spectrum of COVID-19 indicates widespread intraindividual differences in the host immune defense against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The underlying cause of disease heterogeneity is probably multifactorial. However, a rapid early host response is likely critical to generate control of SARS-CoV-2 viremia before spread to the lower respiratory tract and [...]

Hiqa warns indoor spaces create higher risk of Covid-19 spread

By |2020-11-26T15:54:17+00:00November 26th, 2020|

Indoor, high-occupancy and poorly ventilated spaces present an increased risk of Covid-19 transmission, the State’s health watchdog has warned. This is particularly the case where “shouting and singing” and prolonged contact occurs, or where face-coverings are insufficiently used, the Health Information and Quality Authority says. Photo by Startup Stock Photos from Pexels Read more… The [...]

Delirium fairly common in older COVID-19 patients

By |2020-11-26T15:54:15+00:00November 26th, 2020|

A study published today in JAMA Network Open shows that 28% of older COVID-19 patients at seven US emergency departments (EDs) had delirium, putting them at higher risk of an intensive care unit (ICU) stay and death. A research team led by Massachusetts General Hospital scientists found that, of 817 COVID-19 patients 65 and older arriving at EDs, 226 [...]