INTRODUCTION  This calculator determines the number of new COVID-19 infections in a space (classroom, etc.) due to aerosol transmission, accounting for infectious aerosol in the breath of asymptomatic individuals. The aerosols, at sizes 7 microns and below, are emitted from the normal action of breathing and talking — they have lifetimes of hours in air, [...]

MEXICO CITY (Reuters) – Deaths in Mexico from the coronavirus pandemic rose above 35,000 on Sunday, with the Latin American country overtaking Italy for the world’s fourth-highest death total, according to Reuters data. But leftist President Andres Manuel Lopez Obrador said on Sunday that the pandemic was “losing intensity” in Mexico, and blamed what he [...]

As some communities in the United States open K-12 schools, CDC offers the following considerations for ways in which schools can help protect students, teachers, administrators, and staff and slow the spread of COVID-19. Schools can determine, in collaboration with state and local health officials to the extent possible, whether and how to implement these considerations while [...]

High rates of preterm birth and cesarean delivery have been reported in women with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.1 However, studies have inadequate power to assess uncommon outcomes like stillbirth (fetal death ≥24 weeks’ gestation). The UK Obstetric Surveillance System reported 3 stillbirths among 247 completed pregnancies in women with confirmed coronavirus disease [...]

Abstract Although most SARS-CoV-2-infected individuals experience mild coronavirus disease 2019 (COVID-19), some patients suffer from severe COVID-19, which is accompanied by acute respiratory distress syndrome and systemic inflammation. To identify factors driving severe progression of COVID-19, we performed single-cell RNA-seq using peripheral blood mononuclear cells (PBMCs) obtained from healthy donors, patients with mild or severe COVID-19, [...]

As states continue to set records with daily COVID-19 case counts, fatalities due the virus are beginning to creep upward, with Arizona, Texas, Mississippi, California, and Florida all breaking records for average daily fatalities over the past 7 days. And more than 80% of intensive care beds are occupied in Arizona, Alabama, and Georgia. The summer surge [...]

Two new studies have revealed that the rheumatoid arthritis drug tocilizumab is associated with lower death rates in COVID-19 patients receiving mechanical ventilation. Tocilizumab blocks interleukin-6 (IL-6), an inflammatory protein involved in a potential “cytokine storm” that can lead to respiratory failure in coronavirus patients. In the first single-center observational study, published late last week in Clinical Infectious [...]

With the global COVID-19 total just shy of 13 million cases, the World Health Organization (WHO) reported a record high 230,000 cases yesterday, amid warnings from the group that many countries are headed in the wrong direction. The global total today climbed to 12,995,037 cases, and 570,435 people have died from their infections, according to the [...]

Antimicrobials are important medical therapies that have come to define modern medicine. Their unnecessary use and overuse can promote the emergence of antimicrobial resistance (AMR) – that is, the ability of organisms to overcome the effects of the drugs designed to kill them. The spread of antimicrobial-resistant organisms (AROs), sometimes referred to as superbugs, jeopardizes [...]

Don’t be discouraged if you’re not a quick walker. A new study suggests that total daily steps — and not how many steps you take per minute — are related to a lower risk of death. The results were published in the March 24/31, 2020, issue of JAMA. Researchers examined data from 4,840 people, average age 57, [...]