
After living for more than 2 years with COVID-19—with over 6·2 million confirmed deaths (but probably many more, with an estimated 20 million excess deaths) and over 510 million confirmed cases—the world is at a critical point. The omicron wave, with its high transmissibility and milder course than previous variants, especially for people who are fully vaccinated and without comorbidities, is abating in many countries. Restrictions are being relaxed, and people are slowly returning to pre-pandemic activities, including gatherings, office-based working, and cultural events. Mask mandates are being lifted in many countries. Testing and surveillance have decreased and travelling is recommencing widely. People are understandably exhausted and want to forget about the pandemic. This would be a grave mistake.
First, the pandemic situation is not the same everywhere in the world. China, for example, continues to employ its so-called dynamic zero COVID strategy of mass testing, quarantining of those testing positive, and lockdown of districts or even whole cities (most recently Shanghai). Chinese authorities have been harshly and ruthlessly implementing these measures, without much consideration for human costs. The goal is, according to Chinese officials, to avoid further spread, to protect the health system, and to avert deaths. The problem is that older and vulnerable people are often not fully vaccinated, and the efficacy of the licensed vaccines is suboptimal. For China, the top priority must be to accelerate an effective vaccination strategy. The current approach is not a long-term solution for Chinese people.
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