Atopic dermatitis (AD) is a form of eczema. AD affects up to 13% of children and 10% of adults, with an annual treatment cost of $5.3 billion in the U.S. alone.

"We often think of eczema as a dry-skin condition and treat mild cases with moisturizers," said corresponding author Tamia Harris-Tryon, M.D., Ph.D., Assistant Professor of Dermatology and Immunology at UTSW. "Here, we're showing that a gene that's important for making sex hormones seems to play a role in the skin making its own moisturizers. If we could alter this gene's activity, we could potentially provide relief to eczema patients by helping the skin make more oils and lipids to moisturize itself."

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