In utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts

Highlights

 

•    In utero exposure to BPA was prevalent from 1999 to 2010.
•    In utero exposure to BPA may increase the risk of asthma and wheeze among school-age girls.
•    No evidence of an association with lung function at school-age nor wheezing patterns across childhood.

Abstract

Background

In utero exposure to bisphenols, widely used in consumer products, may alter lung development and increase the risk of respiratory morbidity in the offspring. However, evidence is scarce and mostly focused on bisphenol A (BPA) only.

Objective

To examine the associations of in utero exposure to BPA, bisphenol F (BPF), and bisphenol S (BPS) with asthma, wheeze, and lung function in school-age children, and whether these associations differ by sex.

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