Could lenacapavir be the answer for people with multidrug-resistant HIV infection? Principal investigator Sorana Segal-Maurer discusses the promising trial results in this challenging cohort (Interview part 1).

There have been myriad advances in HIV treatment options. Injectable, long-acting HIV therapies, once a pipe dream, are now approved and available.

However, treatments for people living with multidrug-resistant human immunodeficiency virus type 1 (HIV-1) are far more limited. People with difficult-to-treat HIV or a history of treatment failure have substantial treatment needs.

Lenacapavir, a first-in-class capsid inhibitor, has potential to fulfill this need. Today, research from the ongoing phase 3 CAPELLA trial was published in The New England Journal of Medicine. Sorana Segal-Maurer, MD, the principal investigator and lead author of the paper, sat down with Contagion to discuss the significance of these results.

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