Non-genetic tumor diversity contributes to treatment failure in cancer patients

Leonard Harris, assistant professor of biomedical engineering, led a team of researchers from Vanderbilt University that has shown how an in vitro model of tumor heterogeneity, or diversity, resolves three different sources of cell state variability in cancer cells. The paper has been published in PLOS Biology.

A heterogeneous  is a tumor that is made up of many different types of . Often, the  have different types of  and co-exist within a tumor. The diversity of the tumor is what makes  difficult to treat.

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