Patient-specific mathematical model determines how aneurysm shape and size influence growth and rupture

Cerebral aneurysms appear in 5% to 8% of the general population. The blood vessel rupture and resultant blood leakage within the brain can lead to severe stroke or fatal consequences. More than one quarter of patients who experience a hemorrhagic stroke die before reaching a health care facility.
 

Predicting the rupture of aneurysms is crucial for medical prevention and treatment. Researchers from the Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, and the Indian Institute of Technology Madras, developed a patient-specific mathematical model to examine what  parameters influence rupture risk prior to surgery. Their study is published in Physics of Fluids.

Aneurysms occur when the weakest point of a blood vessel thins, expands, and, after a certain limit, bursts. In the case of cerebral aneurysms, such as internal carotid artery bifurcation aneurysms, blood leaks into the intracranial cavity

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