Risk of severe coronavirus disease 2019 (COVID-19) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increased in patients with certain comorbidities, including chronic obstructive pulmonary disease (COPD). By contrast, epidemiological data from many (but not all) countries indicate a low prevalence of asthma among patients with severe COVID-19. This reduced risk of severe COVID-19 may apply specifically to patients with the type 2 asthma endotype, which is most common in childhood asthma.

It is now well established that several comorbidities comprise an increased risk for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coronavirus disease 2019 (COVID-19) severity or COVID-19-associated mortality. Among them are diabetes, hypertension, metabolic syndrome, obesity and coronary heart disease. Surprisingly, however, patients with chronic inflammatory lung disease, particularly bronchial asthma or chronic obstructive pulmonary disease (COPD), show a more complex association with SARS-CoV-2 infection and COVID-19.

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