The World Health Organization has reported 169 cases of acute hepatitis of unknown origin in kids ages 1 month to 16 years old.¹The reporting comes as of April 23.

One death has occurred, and 17 patients have required liver transplantation.

According to the WHO report, cases have been reported in the United Kingdom of Great Britain and Northern Ireland (the United Kingdom) (114), Spain (13), Israel (12), the US (9), Denmark (6), Ireland (<5), The Netherlands (4), Italy (4), Norway (2), France (2), Romania (1), and Belgium (1).

The Adenovirus has been detected in at least 74 cases, and WHO has said this could represent a rare outcome occurring at levels not previously detected that is now being recognized due to increased testing. The WHO said that although this virus is potential cause, investigators say is does not fully explain the severity of the ongoing cases. Specifically, infection with adenovirus type 4, which 18 patients have been identified as F type 41, does not typically present with this severity. Adenovirus 41 has not been shown to cause hepatitis in healthy children.