Ebola virus disease - Democratic Republic of the Congo

Outbreak at a glance

On 21 August 2022, the Ministry of Health (MoH) of the Democratic Republic of the Congo announced that a new laboratory-confirmed case of Ebola Virus Disease (EVD) had been detected in Beni health zone in the province of North Kivu. The case, a 46-year old woman who had co-morbidities, died on 15 August 2022 after being hospitalized for 23 days. Oropharyngeal secretion samples were taken after death on 15 August 2022 and tested positive for EVD. The body was buried before the EVD results were known. Field investigations are ongoing to identify hospital and community contacts. The last EVD outbreak in the Democratic Republic of the Congo was in Equateur province and declared over on 4 July 2022.

Outbreak overview

On 21 August 2022, the Ministry of Health (MoH) of the Democratic Republic of the Congo announced that a new laboratory-confirmed case of Ebola Virus Disease (EVD) had been detected in a 46-year-old woman living in the city of Beni, in the province of North Kivu.

The case was hospitalized and treated for 23 consecutive days—from 23 July to 15 August 2022—for symptoms thought to be related to her known co-morbidities, including cough, headache, polyarthralgia (joint pain), and physical asthenia (general fatigue). The patient died in hospital on 15 August 2022 and the body was returned to the family for burial. To date, there is no information on the Ebola vaccination status of the deceased case.

On 15 August 2022, a sample of the oropharyngeal secretions was taken from the body and tested positive by reverse transcription polymerase chain reaction (RT-PCR) at the National Institute for Biomedical Research (INRB), Beni. For quality control purposes, the sample was then tested at the Rodolphe Mérieux INRB Laboratory in Goma, which confirmed the results by RT-PCR on 16 August 2022. The body was returned to the family prior to receiving the laboratory results and subsequently buried on 16 August 2022.

A total of 134 hospital contacts (60 health care personnel and 74 co-patients) have been identified. As of 24 August, nine family contacts have also been identified. There are ongoing investigations by response teams in the health facility where the patient was being treated, as well as in the community.

The sequencing carried out at the Rodolphe Mérieux Laboratory of INRB in Goma confirmed this case is genetically linked to the 2018-2020 outbreak in North Kivu, Ituri and South Kivu provinces (Ebola Zaire strain) and not a new spillover event. (For more information on this outbreak, please see the Disease Outbreak News published on 26 June 2020). Samples were also sent to INRB-Kinshasa for genomic sequencing.

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