In the Press

Researchers discover a new type of RNA that inhibits a broad range of viral infections

RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many types of non-living viruses, however, carry their genetic information in a double-stranded form of RNA (dsRNA). When the human immune system detects the presence of this foreign RNA, it sounds the alarm by increasing the production of protective cytokines called interferons (IFN), which activate the innate immune response against viral invaders.


Penicillin allergy labels associated with worse outcomes in bacterial pneumonia

Within 30 days of a bacterial pneumonia diagnosis, 69.2% of patients with a penicillin allergy label and 56.2% of those without a label were hospitalized.


Researchers identify flu-fighting pathways and genes essential for influenza a immune defense

Researchers have identified the gene TDRD7 as a key regulator against influenza A virus (IAV), which causes respiratory tract infections in 5 to 20 percent of the human population. These findings could facilitate the development of novel therapeutic interventions against influenza virus infection. The study, led by the Icahn School of Medicine at Mount Sinai in collaboration with other institutions, was published in Science Advances on October 5.


Mortality Associated with Ambient PM2.5 Exposure in India: Results from the Million Death Study

Studies on the extent to which long-term exposure to ambient particulate matter (PM) with aerodynamic diameter ≤2.5μm≤2.5μm (PM2.5PM2.5) contributes to adult mortality in India are few, despite over 99% of Indians being exposed to levels that the World Health Organization (WHO) considers unsafe.


Opportunistic pathogens enriched in showerhead biofilms

The environments we humans encounter daily are sources of exposure to diverse microbial communities, some of potential concern to human health. In this study, we used culture-independent technology to investigate the microbial composition of biofilms inside showerheads as ecological assemblages in the human indoor environment. Showers are an important interface for human interaction with microbes through inhalation of aerosols, and showerhead waters have been implicated in disease.


COVID vaccines in pregnancy tied to lower risk of NICU stay, stillbirth

COVID-19 vaccination during pregnancy was linked to a lower risk of neonatal intensive care unit (NICU) admission, stillbirth, and maternal SARS-CoV-2 infection and no additional risk of preterm birth, small for gestational age (SGA), low Apgar score, cesarean delivery, postpartum hemorrhage, or chorioamnionitis, finds a systematic review and meta-analysis published yesterday in JAMA Pediatrics.


An emergency department-based ICU improves survival without raising costs

In the study, cost per visit for critically ill patients decreased by more than 20%.


What were the historical reasons for the resistance to recognizing airborne transmission during the COVID-19 pandemic?

The question of whether SARS-CoV-2 is mainly transmitted by droplets or aerosols has been highly controversial.


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