In the Press

Evotec SE (Frankfurt Stock Exchange: EVT, MDAX/TecDAX, ISIN: DE0005664809; NASDAQ: EVO) today announced that the U.S. Department of Defense (“DOD”) has awarded Evotec’s Seattle-based subsidiary, Just – Evotec Biologics, Inc. a contract valued up to $ 49.9 m for the rapid development of monoclonal antibody (“mAb”)-based drug product prototypes targeting plague. Plague, an infectious disease caused by the bacterium Yersinia pestis (“Y. pestis”), is one of the designated targets of interest under the DOD’s Accelerated Antibodies Program.

Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development. The once radical idea that such changes in gene expression can be inherited now has a growing body of evidence behind it, but the mechanisms involved remain poorly understood.

Because epidemiological studies have yielded different results, the association between exposure to fine particulate matter less than 2.5 microm in aerodynamic diameter (PM(2.5)) and acute events of cardiovascular diseases (CVD) is unknown.

In vitro fertilization (IVF) using frozen embryos may be associated with a 74% higher risk of hypertensive disorders in pregnancy, according to new research published today in Hypertension. In comparison, the study found that pregnancies from fresh embryo transfers—transferring the fertilized egg immediately after in vitro fertilization (IVF) instead of a frozen, fertilized egg—and pregnancy from natural conception shared a similar risk of developing a hypertensive disorder.

Three doses of an mRNA COVID-19 vaccine during a time of Omicron variant predominance were tied to a 59% lower odds of hospitalization than two doses, although protection waned over time, finds a US case-control study published late last week in JAMA.

The first large, real-world study of the effectiveness of mRNA COVID-19 vaccines during pregnancy found these vaccines, especially two initial doses followed by a booster, are effective in protecting against serious disease in expectant mothers whether the shots are administered before or during pregnancy.

Uganda's health ministry today reported a steady surge in Ebola Sudan cases in the past few days, bringing the total to 36 of which 23 (64%) have proved fatal.

Indoor surfaces are paradoxically presumed to be both colonized by pathogens, necessitating disinfection, and “microbial wastelands.” In these resource-poor, dry environments, competition and decay are thought to be important drivers of microbial community composition.

Nina Notman talks to the experts about what is needed to remove pollutants and even infectious diseases from the air inside our homes, schools and offices

The impacts of air pollution on human health, economies, and agriculture differ drastically depending on where on the planet the pollutants are emitted, according to a new study that could potentially incentivize certain countries to cut climate-changing emissions.