The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host factors. Recent advances point to cellular senescence, an ageing-related switch in cellular state, as a critical regulator of SARS-CoV-2-evoked hyperinflammation. SARS-CoV-2, like other viruses, can induce senescence and exacerbates the senescence-associated secretory phenotype (SASP), which is comprised largely of pro-inflammatory, extracellular matrix-degrading, complement-activating and pro-coagulatory factors secreted by senescent cells.
An outbreak of monkeypox virus infections in non-endemic countries was recognised on May 12, 2022. As of September 29, more than 67 000 infections have been reported globally, with more than 3400 confirmed cases in the UK by September 26.
Seasonal moisture distributions in building envelopes with different orientations.
Airborne transmission of respiratory aerosols carrying infectious viruses has generated many concerns about cross-contamination risks, particularly in indoor environments.
The Food and Drug Administration (FDA) today announced that it has authorized for emergency use updated bivalent (two-strain) COVID boosters for children as young as 5, and shortly after, the Centers for Disease Control and Prevention (CDC) announced its recommendation, which paves the way for the shots to be given.
During 2020–2021, countries in Latin America and the Caribbean reported clinical emergence of carbapenemase-producing Enterobacterales that had not been previously characterized locally, increased prevalence of carbapenemases that had previously been detected, and co-production of multiple carbapenemases in some isolates.
Stillbirth is a recognized complication of COVID-19 in pregnant women that has recently been demonstrated to be caused by SARS-CoV-2 infection of the placenta.
SAN JUAN, Puerto Rico (AP) — A nonprofit organization on Tuesday called on Haiti’s government to release certain inmates amid a swift rise in cholera cases throughout the country’s severely crowded prison system and dwindling supplies of clean water.
Two studies published today reveal new findings on long COVID, with one showing a possible role for cardiopulmonary exercise testing (CPET) for the evaluation of persistent symptoms, and the other finding a link between symptomatic infection and poor quality of life and reduced ability to complete daily activities.
In addition to new, updated COVID-19 vaccines and lifesaving treatments, improving indoor air quality within the buildings we use every day is an essential part of the Biden Administration’s plan to manage COVID-19 this fall and winter.