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Chronic airway diseases including chronic obstructive pulmonary disease (COPD) and asthma are heterogenous in nature and endotypes within are underpinned by complex biology. This study aimed to investigate the utility of proteomic profiling of plasma combined with bioinformatic mining, and to define molecular endotypes and expand our knowledge of the underlying biology in chronic respiratory diseases.
When we talk about antibodies against COVID-19, we tend to mean the so-called neutralizing antibodies, that offer protection by blocking the virus from invading our cells. Now, a new study from Lund University in Sweden has revealed that non-neutralizing antibodies may also be important in providing protection against COVID.
As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants, which cause COVID-19.
This study has two goals. The first is to explain the geo-environmental determinants of the accelerated diffusion of COVID-19 that is generating a high level of deaths. The second is to suggest a strategy to cope with future epidemic threats similar to COVID-19 having an accelerated viral infectivity in society. Using data on sample of N = 55 Italian province capitals, and data of infected individuals at as of April 7th, 2020, results reveal that the accelerate and vast diffusion of COVID-19 in North Italy has a high association with air pollution of cities measured with days exceeding the limits set for PM10 (particulate matter 10 μm or less in diameter) or ozone.
Chris Birch used to dread late afternoon meetings at the old Stretford office of Hilson Moran, a Manchester engineering consultancy. “You’d be sat in a meeting for three hours, feeling slightly headachy, tired and stuffy,” says Birch, the company’s head of sustainability. Outdoors, when very polluted, you can see and taste and smell it. But indoors, you often can’t detect what’s there - Noakes
Both rare and commonly observed differences in the DNA letters strung along a person's chromosomes can explain about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD), according to a new study led by scientists at the Icahn School of Medicine at Mount Sinai.
In the latest global COVID-19 developments, clusters of new local cases prompted lockdowns in a few northern areas, and France-based Valneva reported positive results for its vaccine when compared to the AstraZeneca-Oxford vaccine.
Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research.
The COVID-19 pandemic has been associated with weight gain among adults,1 but little is known about the weight of US children and adolescents. To evaluate pandemic-related changes in weight in school-aged youths, we compared the body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) of youths aged 5 to 17 years during the pandemic in 2020 to the same period before the pandemic in 2019.