In the Press

Researchers have shown for the first time in mice that heart problems associated with the flu are not caused by raging inflammation in the lungs, as has long been predicted.

More than 40 million Americans take statins, the most common type of prescription drug. While statins have been shown to effectively lower cholesterol levels and reduce the risks of stroke and heart attack, they do not work the same for everyone, and side effects of statin use include an increased risk of developing type 2 diabetes.

Scientists are fusing sequencing, chemistry and imaging techniques to probe interactions between pathogens and their host cells.

Today, air pollution is one of the most important environmental problems in world cities.1 In the past few decades, the findings of epidemiological studies have shown that there is a significant relationship between human health and air pollution.2, 3

Rep. Don Beyer (D-VA), who chairs Congress’ Joint Economic Committee, today announced the introduction of the Airborne Act, legislation that would incentivize non-residential building owners to conduct indoor air quality assessments (IAQ) and upgrade their ventilation and air filtration systems. The bill introduction followed a sharp uptick in workers returning to in-person work in April, according to the Bureau of Labor Statistics.

Neurodegenerative diseases damage and destroy neurons, ravaging both mental and physical health. Parkinson's disease, which affects over 10 million people worldwide, is no exception. The most obvious symptoms of Parkinson's disease arise after the illness damages a specific class of neuron located in the midbrain. The effect is to rob the brain of dopamine—a key neurotransmitter produced by the affected neurons.

Gao, Y., Fu, J. S., Drake, J. B., Lamarque, J.-F., and Liu, Y.: The impact of emission and climate change on ozone in the United States under representative concentration pathways (RCPs), Atmos. Chem. Phys., 13, 9607–9621, https://doi.org/10.5194/acp-13-9607-2013, 2013.

Antimicrobial resistance (AMR) represents a significant source of morbidity and mortality worldwide, with expectations that AMR-associated consequences will continue to worsen throughout the coming decades.

Introduction Respiration promotes growth and proliferation of bacterial cells [1]. Energy acquisition through respiration relies on the metabolism of exogenously acquired substrates and the presence of terminal electron acceptor molecules to generate chemical energy, which is stored in the form of ATP to power cellular processes required for growth. Although not considered canonical virulence factors, metabolism and energy generative processes are required by pathogens to thrive during infection. Here we investigate respiration as a potent driver of replication during infection by the bacterial gastrointestinal pathogen Vibrio cholerae [2].

Could lenacapavir be the answer for people with multidrug-resistant HIV infection? Principal investigator Sorana Segal-Maurer discusses the promising trial results in this challenging cohort (Interview part 1).