In the Press

A change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of more aggressive cancerous cells, according to a recent Northwestern Medicine study published in Proceedings of the National Academy of Sciences.

School districts have yet to use billions in federal funding for new and existing technology to clear the air.

Importance  Because transmission of ocular strains of Chlamydia trachomatis is greatest among preschool-aged children, limiting azithromycin distributions to this age group may conserve resources and result in less antimicrobial resistance, which is a potential advantage in areas with hypoendemic trachoma and limited resources.

Many diseases linked with ethnic health disparities associate with changes in microbial communities in the United States, but the causes and persistence of ethnicity-associated microbiome variation are not understood.

Researchers used a recently developed method of wastewater genomic surveillance to detect SARS-CoV-2 infections on the University of California, San Diego (UCSD), campus during 10 months of the pandemic. The approach identified viral variants of concern as early as 2 weeks before the variants showed up in clinical tests, the team recently reported in Nature.

A central issue in assessing the airborne risk of COVID-19 infections in indoor spaces pertains to linking the viral load in infected subjects to the lung deposition probability in exposed individuals through comprehensive aerosol dynamics modelling.

Doctors could one day diagnose and characterize early stage small cell lung cancer (SCLC) with a simple blood test thanks to a transatlantic study led by CRUK Manchester Institute Cancer Biomarker Center researchers at the University of Manchester with a team at Memorial Sloan Kettering Cancer Center in New York published in Nature Cancer.

Researchers at Washington University School of Medicine in St. Louis have found a new druggable pathway that potentially could be used to help prevent Alzheimer's dementia.

Importance  The postacute sequelae of SARS-CoV-2 infection (PASC) has emerged as a long-term complication in adults, but current understanding of the clinical presentation of PASC in children is limited.

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found. This population has been underrepresented in previous clinical trials of asthma therapeutics. The findings were published today in the journal The Lancet.