In the Press

Results of a small, but unique research study, led by researchers from the Seaver Autism Center for Research and Treatment at Mount Sinai and published online in Human Genetics and Genomic Advances, suggest that low-dose ketamine is generally safe, well-tolerated and effective to treat clinical symptoms in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.

A new study by UT Southwestern's Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer. The finding, published in Nature Communications, could eventually be used to develop new strategies to augment the anti-tumor effect of cancer immunotherapies, the study authors said.

Risk of severe coronavirus disease 2019 (COVID-19) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increased in patients with certain comorbidities, including chronic obstructive pulmonary disease (COPD). By contrast, epidemiological data from many (but not all) countries indicate a low prevalence of asthma among patients with severe COVID-19. This reduced risk of severe COVID-19 may apply specifically to patients with the type 2 asthma endotype, which is most common in childhood asthma.

Sleeping with either windows or doors open improved subjective-rated sleep quality.

Cardiac symptoms are increasingly recognized as late complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in previously well individuals with mild initial illness, but the underlying pathophysiology leading to long-term cardiac symptoms remains unclear.

A team of researchers from the Instituto Gulbenkian de Ciência (IGC) revealed that cells of the brain can detect the presence of malaria parasites in the blood, triggering the inflammation underlying cerebral malaria. This discovery brought to light new targets for adjuvant therapies that could restrain brain damage in initial phases of the disease and avoid neurological sequelae.

In a new publication in Nature Communications, Martin Rottenberg and Ruining Liu, professor and Ph.D. student at the Department of Microbiology, Tumor and Cell Biology, explain how T cell protection against tuberculosis is controlled by their oxygen responses.

Drier indoor air may keep viruses active longer, increasing risk of long-range airborne transmission

Washington, D.C., 3 September 2022 (PAHO) - The Pan American Health Organization (PAHO) has been informed by the Argentina Ministry of Health that legionella has been confirmed as the cause of a cluster of pneumonia cases associated with a health clinic in the province of Tucuman, Argentina.

Persistent COVID-19 sequelae could have global, public health ramifications. We therefore aimed to describe sequelae presenting more than 180 days after COVID-19—focussing on several organ systems, general health, and laboratory parameters—in non-hospitalised, unvaccinated, young adults.